He is still sick at the moment and has not trained yet.
If the Germany global doesn't recover in time, the boss could field Nacho Monreal alongside Rob Holding and Per Mertesacker in a three with Kieran Gibbs as a left wing-back.
However, Ferguson - who rivalled Wenger in the top-flight during his storied career with Manchester United - says that the events of this season can not overshadow the Frenchman's work at the Emirates.
"Some clubs are stronger than us yes, but now I believe we are in a position to compete and we have a strong enough basic squad to compete at the top level".
He added: "It is annoying but we had a spell during the season that was hard and it was hard for me in my personal situation".
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Per Mertesacker is also available for the FA Cup final, however the former German global only made his return to the Arsenal first team from injury yesterday, playing the final 30 minutes of the season.
The 67-year-old has just two matches remaining before his current contract expires but has yet to announce publicly if he will sign fresh terms.
Asked if his Arsenal reign would extend from 21 years to 22 or 23, Wenger said: "I can not answer that question at the moment".
"No [the result will not have an impact]".
"No, why?" he said. He opens the game up and says: "You have a shot, we have a shot, best team wins". You just want to win it. But Wenger said he is not focused on his own place in history. But knowing the player, knowing his character and commitment to the club - which I don't question at all - he will do absolutely everything to be fit for Saturday.
The France centre-back was also sent off during the second leg of Arsenal's last-16 Champions League clash with Bayern Munich this season as they went down to a 10-2 aggregate loss.
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"My situation is very clear: I have two more years' contract with the club", said Conte on the eve of the FA Cup final against Arsenal .
"The team has given so much and they really want to win something this season".
"Alex Oxlade-Chamberlain is in contention because he is back in training".
Sanchez still faces a fitness test, but Wenger sounded confident that the Chile worldwide will be able to start.
"That is my mindset, no matter what happens or what is facing me on Saturday, I am going to go for it".
It means Wenger has a big decision to make at the back on Saturday.
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