Days on from another draw at home in the Premier League, Jose Mourinho appears to have put all his Champions League eggs in one Europa League basket.
Shaw has had some issues to overcome this term and struggled for game time, although the England worldwide had managed to force his way back into Mourinho's plans in recent weeks.
Paul Pogba of Manchester United celebrates scoring his sides first goal with Michael Carrick during the Premier League match between Swansea City and Manchester United at Liberty Stadium on November 6, 2016 in Swansea, Wales.
Speaking ahead of United's Europa League semifinal first leg at Celta Vigo on Thursday, Mourinho revealed his plan to manage his banged up squad as the games continue to come thick and fast.
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Press Association Sport understands the left-back was due to see a specialist after scans showed ligament damage in his left foot, which Mourinho says will bring his campaign to a premature end.
"Because of that we've had players that [have] had to play 750, 800 minutes of football and we pay the price".
Celta's top scorer Iago Aspas was anonymous before the break, but started the second-half brightly and saw flicked header float just wide.
Sunday's game is arguably bigger for Wenger, who has still yet to announce whether he will sign a new deal to remain at Arsenal beyond the end of the current season. The availability of Lacazette and Tolisso gives Ajax coach Peter Bosz more to think about as he prepares his defense to face one of the most attack-minded sides in Europe.
The Switzerland worldwide took some time to become fully integrated in the Premier League, although he has slowly improved in an Arsenal jersey. Another defender, Daley Sinkgraven, and striker Bertrand Traore are in doubt with injuries.
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He added, "I believe in good preparation and good planning, if you've done that then the 25 seconds will go". When Roger Bannister broke the four-minute mile in 1954, the World Record for the Marathon stood at 2:18:34.
"At the moment, injuries are a big problem and the team is looking more exhausted by the day", he said.
"You know, when you are such a long time at a club like I am, like Ferguson was, it is a little bit like when you have children", he said.
Celta's focus on scoring means the team has exposed its defense to some beatings this season, while also producing major upsets.
United are looking to join an elite group of clubs who have won the Champions League (formerly European Cup), the European Cup Winners' Cup, and the Europa League (formerly UEFA Cup).
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Louis and the Black River, which cuts through southeast Missouri and northeast Arkansas - are dreading what they'll find. The high water marks of the two worst floods in Alton's history are painted on the side of the door at right.
Celta, by contrast, have had the luxury of resting up Eduardo Berizzo's preferred XI for the majority of their recent La Liga games as the Galicians concentrate on trying to win a first ever major trophy.