However, should Real pick up at least a point against Celta, then the destiny of the championship would be back in their own hands as they prepare to head to Malaga for Sunday's finale.
In a different match, Real Madrid register 4-1 victory over Sevilla and that was enough to keep Los Blancos level on points with the Blaugrana after Week 37. That draw at the Balaidos ended Real Madrid's chances of a treble and Los Blancos would like nothing more than to avenge that cup defeat.
"It is a long road".
"We played with a very good attitude, with a lot of determination and personality", Madrid coach Zinedine Zidane said.
A win or a draw in the match postponed from February because of bad weather will move Madrid past Barcelona into first place going into the weekend's final round of matches.
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"We have one game left and the objective is to win it", he told TV station Movistar.
"It'll be hard because Celta are a good team".
Nacho gave the hosts the lead in controversial fashion as he curled home a quick free kick with the Sevilla defence caught unawares and their protests towards referee Alberto Undiano Mallenco falling on deaf ears.
Ronaldo lashed into the near corner from outside the area to put Real in charge in the 10th minute with a goal that moved him ahead of former England striker Jimmy Greaves as the all-time leading scorer in Europe's top five leagues on 367 goals.
The Frenchman also revealed that midfielder James Rodriguez did not train with the squad, after picking up a knock in their victory against Sevilla last week.so it is unlikely we that we may see the Colombian feature in Real Madrid's starting XI tonight.
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After seeing a delicately chipped effort come off the bar, Jovetic halved the deficit three minutes before half-time with a neat finish from outside the box.
The Cucuta-born attacker applauded all four sides of the stadium as he left the pitch in what would be his final home game should he transfer after three seasons in the Spanish capital.
Despite a revival of fortunes recently, which has seen him score seven goals in his last 10 games, James has been subject to months of speculation linking him with a move overseas, with Manchester United reportedly the most likely suitors. Toni Kroos closed the scoring in the final minutes.
Barcelona kept the pressure on despite a series of defensive absences which meant Brazilian Marlon Santos, 21, was handed a full debut in the Canary Islands.
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