Kerber, 29, has struggled this year, withdrawing from the Madrid Open with a thigh injury and going down in straight sets to qualifier Anna Kontaveit in Rome.
Cutting a troubled figure on court a world away from the feisty player who last season battled her way to two grand slam titles, Kerber lacked the pace and power to trouble a fellow left-hander.
Kerber won the Australian Open and US Open titles a year ago and also reached the final at Wimbledon.
Trump calls for end of the legislative filibuster
Twenty-one percent of voters think it should be made easier to bypass, while 12 percent want it changed to be harder to skirt. Trump has criticized the filibuster before. "Either elect more Republican Senators in 2018 or change the rules now to 51%".
There was nothing positive for Kerber to take from her 6-2 6-2 loss to Ekaterina Makarova as she became the first top seed in the women's draw to lose in the opening round at Roland Garros in the Open era. "That's unbelievable", she said. This also marks the second consecutive year in which the German player has been bounced from the tournament in the first round.
Russian Makarova, ranked 40, won five of the first six games and, although she came under more pressure in the second set, she kept Kerber at arm's length.
"At the end of the match, it was really tough as I knew she wouldn't give it to me - I had to win it".
Four successive breaks of serve followed before Makarova saved seven break points in the crucial eighth game to cause the upset.
Russians said they had potentially "derogatory" information on Donald Trump
An Obama administration official told CNN "This was a five-alarm fire from early on, the way the Russians were talking about him". Sources tell CNN that Russian officials were intercepted by American intelligence boasting of leverage over Trump's inner circle.
"I'm really glad to have made the decision to play here", said 27-year-old Kvitova, who was seriously hurt when she fought off a knife-wielding burglar at her home in the eastern Czech town of Prostejov in December.
The loss opens up the French Open to others such as Simona Halep. The 31st-seeded Vinci, most famous for ending Williams' hopes of a calendar year Grand Slam by beating her in the semifinals at Flushing Meadows in 2015, lost to Rio Olympics gold medalist Monica Puig 6-3, 3-6, 6-2.
Gas prices rise slightly in northern New England
Prices were up three cents in the week leading up to and including Memorial Day weekend to $2.87. Wichita- $2.20/g, down 3.5 cents per gallon from last week's $2.24/g.