A vehicle crash near the Library of Congress on Monday injured a Capitol Police officer and the car's driver, authorities said.
The driver, whose identity has not been released by officials, was charged with assault with a deadly weapon-vehicle, assaulting a police officer (felony), aggravated reckless driving, and no valid permit. All roads except Independence Avenue between Second and Third streets reopened shortly before 3:30 p.m.
Police are searching the "suspicious" vehicle at Second Street SE and Pennsylvania Avenue SE.
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Police have not identified the driver.
The Senate Press Gallery warned on Twitter that there would be "loud noise" while authorities deal with the suspicious auto.
Capitol Police said there was no evidence to indicate any nexus to terrorism.
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Cops used a bomb robot to apporach the vehicle and officers were heard yelling "fire in the hole" before the explosion.
One person was shot and another was stabbed in incidents in Northeast and Southeast Washington.
People were been warned to avoid the area and numerous roads have been closed.
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Police said they were looking for four suspects in the shooting.