Mississippi State welcomes LSU to Starkville, Miss., on Saturday for the first SEC game of the year for each team.
Running back Derrius Guice gained only 76 yards on 15 carries for 76 yards.
LSU tied it at 7 in the second quarter on Darrel Williams' 10-yard touchdown run.
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Rudolph's success resulted in big numbers for the OSU receivers, as well, as four players tallied more than 100 receiving yards. Struggling graduate transfer quarterback Max Browne lasted just over a quarter before being replaced by sophomore Ben DiNucci .
Quarterback Danny Etling was 13-of-29 for 137 yards, as a few of his passes were dropped.
Immediately after the game, Mississippi State coach Dan Mullen met with the media to talk about his program's big win.
After the game, several players said they were embarrassed by the lack of discipline and number of penalties by the Tigers. Aeris Williams added 146 yards for Mississippi State, which rushed for 285 yards in the game.
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In past two losses to LSU, Mississippi State ran for a combined 99 yards.
The beatdown casts serious doubt on the notion that the continuity brought by the Orgeron hire would pay immediate dividends.
The Tigers' depth on both lines is a problem: Once LSU gets a little winded up front offensively and defensively, the dropoff in talent is dramatic. The Bulldogs will get their shot at the Crimson Tide at Davis Wade Stadium in November, but first they'll need to survive a road back-to-back against Georgia and Auburn, plus the rest of a rigorous conference schedule. If any team is going to change that over the next three months, though, it might be Mississippi State.
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Police agencies across the state are working together to make sure things don't get out of hand. But they were surrounded by hundreds of others who said they wanted the statue taken down.