Reports said two Taliban suicide bombers in Humvee trucks targeted the military base.
At least 41 Afghan soldiers were killed in a Taliban attack on an Afghan army camp in the province of Kandahar which began late Wednesday.
Spokesman Dawlat Wazir said that 10 attackers were killed in the clashes. "The base is under ANA (Afghan National Army) control", Waziri added.
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Toryalai Abdyani, the police chief for Paktia province, was also killed in the attack in Gardiz, capital of Paktia province, some kilometers away Kharlachi area of Pakistan.
The attack occurred in Maiwand district of Kandahar, Tolo news reported.
At least 40 servicemen were killed and scores injured in an attack targeting a military base in Afghanistan's Kandahar, global media reported.
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An Afghan security source told AFP that the dead and wounded had been taken to Kandahar's military hospital.
US President Donald Trump vowed earlier this year to stay the course in Afghanistan, America's longest war.
The Western-backed government in Kabul is struggling to beat back insurgents in the wake of the exit of most North Atlantic Treaty Organisation forces in 2014. President Donald Trump and USA officials have accused Pakistan of not preventing militant groups' attacks in Afghanistan from within its territory. Taliban spokesman Qari Yousuf Ahmadi said at least 60 Afghan soldiers were killed and wounded many others, he said.
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On Tuesday morning, they attacked a police training centre in the eastern province of Paktia, killing 48 people, including about 20 civilians.