"Certain Washington politicians choose to fight for foreign countries, but President Trump will always fight for the American people", spokesman Raj Shah said in a statement issued after The Washington Post reported Trump's comments.
The government of Haiti said in a statement it was "deeply shocked and outraged" by Trump's remark - and called it "racist".
But conclusions about Trump's mental acuity were not expected.
The comment was "clearly" racist, said Ebba Kalondo, spokeswoman for AU chief Moussa Faki.
"Given the historical reality of how many Africans arrived in the United States as slaves, this statement flies in the face of all accepted behaviour and practice", said spokesperson Ebba Kalondo. He wants more funding for the wall, which is symbolic, yes, but that's exactly the point: As Frank Sharry of America's Voice puts it to me, the wall is a "middle finger to Latin America", a statement that "we don't want your kind".
He later tweeted, "this was not the language used" but privately defended his remarks, according to a source who spoke to Associated Press.
Chris Christie gives final State of the State address
New Jersey has one of the worst-funded pensions in the country, with a liability estimated at about $80 billion to $90 billion. Christie was a short-list finalist to be Trump's running mate, before Trump picked now-Vice President Mike Pence.
The president spent Thursday evening making a flurry of calls to friends and outside advisers to judge their reaction to the tempest. Rep. Cedric L. Richmond (D-La.), chairman of the Congressional Black Caucus, said on Twitter that Trump's remarks "are further proof that his Make America Great Again Agenda is really a Make America White Again agenda".
CNN's Don Lemon opened CNN Tonight by saying: "The President of the United States is racist".
"You can not dismiss entire countries and continents as "shitholes", whose entire populations, who are not white, are therefore not welcome", said United Nations human rights spokesman Rupert Colville.
Botswana's foreign ministry summoned the U.S. ambassador in protest and called the comments "highly irresponsible, reprehensible and racist".
"The remarks dishonour the celebrated American creed and respect for diversity and human dignity".
Trump a year ago ended the Deferred Action for Childhood Arrivals program, which provided protection from deportation and the ability to legally work in the country.
Zainab killer to be arrested within 36 hours: LHC
Lahore High Court (LHC) Chief Justice Mansoor Ali Shah took notice of the murder and sought report from the Punjab government. Zainab had left her house in the Road Kot area for her maternal aunt's a few minutes away for religious lessons on January 4.
Social media users across the continent posted images of modern skylines and handsome nature from their countries with the hashtag "s***hole". How many examples do you need of this?
Not all who were offended by what Trump said took the step to call him a racist. And I told him we had an agreement and I wanted to present it to him.
Maybe. He's definitely putting something first, but it's not the America described in the Declaration of Independence (where "all men are created equal') or the Pledge of Allegiance ("one nation, under God, indivisible") or on the base of the Statue of Liberty ("Give me your exhausted, your poor, Your huddled masses yearning to breathe free")".
The US leader underwent a routine physical test on Friday amid growing questions over his mental health and fitness for office.
The criticisms were a part of a worldwide outcry against Trump's remarks, which the president denied saying at a private meeting with lawmakers in the White House on Thursday.
But the president has to know that even if video footage of the comment existed, there wouldn't be any political consequences for him. Tom Cotton of Arkansas and David Perdue of Georgia, said they "do not recall" Trump's derogatory comments about Africa.
Jack Wilshere and Aaron Ramsey in contention for Arsenal's clash with Bournemouth
Aaron Ramsey is back in the Arsenal squad following a hamstring issue, but Mesut Ozil (knee) was rated as only "50-50" by Wenger. Watch a preview of Sunday's Premier League fixtures including Bournemouth v Arsenal.