The France midfielder may well return to the starting line-up against Chelsea this Sunday after Herrera aggravated a muscle injury in Seville, with Mourinho expecting the midfielder to miss a "few weeks".
And when asked about the Frenchman potentially being on the bench again this weekend, the Blues boss said, "We are talking about a top player, about a fantastic player".
"Every coach has to find the right way to manage him".
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This season has seen plenty of Jose Mourinho's conservative approach in big away games, as his team have travelled to Anfield, Wembley, the Ramon Sanchez Pizjuan and failed to score.
But the United manager has also reminded his players they must all earn his trust if they want to play and pointed to 21-year-old Scott McTominay, who started instead of Pogba against Sevilla, as an example.
After the West Ham game, Liverpool have only 10 league matches left and with the exception of Manchester United and Chelsea, all of those games are against teams in ninth place or below.
That has left the others battling for a top four spot with just four points separating Manchester United in second and Tottenham in fifth. They don't have shin pads, strapping, the shirt.
"Sometimes players take five minutes to be ready".
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Initially, Mourinho had spoken more generally about United vs Chelsea fixtures when asked about his head-to-head with Conte.
When asked why Lukaku has been unable to score for United against any teams in the top eight, Mourinho replied: "I don't know but I am not anxious - 21 goals is not bad at all".
The two managers have repeatedly indulged in public insults and war of words but somehow, Mourinho chose to remain tight-lipped this time around.
From the moment Conte's Chelsea thrashed Mourinho's Manchester United 4-0 to kickstart their 2016-17 Premier League title charge, a simmering tension has existed between the pair, who both won the Premier League in their first season in England-and both with the London side.
Mourinho had previously suggested that Herrera had a "bad injury" as a result of Wednesday's clash, and that the medical staff acted in error in passing him fit for last week's FA Cup game against Huddersfield.
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