We're now going to see what happens when Wall Street has the flu, says one market watcher. European shares closed down more than 2 per cent, and losses for the MSCI 47-country world index broke $US4 trillion.
In Tokyo the Nikkei 225 index rose 1.1 percent.
The index closed trading 1,177 points lower, erasing all gains for the year and only two stocks finishing higher.
The Dow Jones industrial average plunged more than 1,000 points as a weeklong market swoon continued.
The biggest drop in the Dow Jones was ExxonMobil, which went down more than 6%. "It can take two to three weeks to work through the system".
Senate to vote on 2-year, $400B budget deal ahead of deadline
The deal, agreed upon by both the Democratic and Republican leaders of the Senate , was immediately welcomed by the White House. Dreamers were shielded from deportation under the Obama-era programme called Deferred Action for Childhood Arrivals ( Daca ).
Two days of steep losses have erased the US market's gains from the start of this year, ending a spate of record-setting calm for stocks. At its worst on Monday, the Dow was down more than 1,500 points.
Since the bottom fell out of US equities on Monday, stocks here and across the globe have been in disarray.
It's the fourth correction for the index since the bull market began in March 2009, according to Bespoke Investment Group.
Analysts have also been saying the market has gotten much too expensive after a huge run-up over the a year ago and has been long overdue for a pullback.
Twitter had a banner day, soaring 12 percent after turning in a profit for the first time. That came during a 15-minute stretch where the 30-stock index lost 700 points and then gained them back.
Man Utd, Real Madrid target opens up over £95m summer exit rumours
Club president Florentino Perez is hellbent on signing "Galactico's" in the summer, and Lewandowski certainly fits the bill. Well, reports suggested the Polish striker harbours ambitions of playing for the Spanish giants.
Shares tumbled in Asia on Tuesday after a wild day for US markets that resulted in the biggest drop in the Dow Jones industrial average in six and a half years. The market tumbled right from the opening bell. The losses were steady, unlike the sharp swings seen over the past few days.
Oil prices were down after data showed US crude output had reached record highs and the North Sea's largest crude pipeline reopened following an outage. The 10-year yield ended the day at 2.837 percent.
On Thursday, all 11 major S&P sectors finished lower, with financials and technology the worst-performing groups. The yield on the 10-year note was as low as 2.04 percent as recently as September.
USA crude fell 1.2 per cent to settle at $US63.39 a barrel while Brent dropped 1.1 per cent to settle at $US66.86.
Stocks are sliding further on Wall Street, putting the market on track for its second big weekly drop in a row. Microsoft and JPMorgan Chase each lost 1.7 percent. The dollar index last rose 0.13%, with the euro up 0.06% to $1.2384.
The S&P 500 fell 6 percent Friday and Monday, and it's down 6.6 percent from the recent record high it set on January 26.
Human eggs grown in lab for the first time in infertility 'breakthrough'
We are working to optimize the conditions that support the development of the egg and study their health. Telfer admits far more research is necessary, and hopes to get regulatory approval for future research.