Better HPV test preventing cervical cancer than Pap smear

Share

Patients with breast cancer may be missing out on genetic tests that could pinpoint the ideal treatment regimen, despite current practice guideline recommendations, Reuters reported. But according to the study, cumulative CIN2+ incidence was similar in the two groups after the end of the trial at 72 months.

More women were referred for colposcopy after HPV tests at the start of the study: 57 per 1,000 women compared with 30.8 per 1,000 women after smear tests - but the reverse was true at 48 months. For women under 25, the Task Force suggests use of Pap test alone because many of them are infected with HPV.

Most medical groups have recommended that women in the United States get both the HPV test and the Pap smear, a practice called "co-testing", and many medical doctors are urging this practice continue, like Dr. Dena Grayson, who brought it up on Twitter.

A study from Canada found that an initial test for human papilloma virus (HPV), which causes nearly all cases of cervical cancer, led to the discovery of more pre-cancerous lesions than were found with conventional smear tests.

Even if guidelines do change for women over 30, the Pap smear is still important for women ages 21-29.

Henderson: I'd step up to take another penalty
Gareth Southgate is juggling injury concerns ahead of a World Cup quarter-final that the England manager ... will to just start his side. "I very of him, are of and me a of doubt is of best in league in and only to better".

Most cervical cancers are caused by a particular strains of the Human papillomavirus, or HPV.

Schmeler often works in Latin America where, in countries like El Salvador, cervical cancer is one of the most common cancers in women primarily due to poor screening programs.

In an accompanying editorial, L. Stewart Massad, MD, of the Washington University School of Medicine in St. Louis, argued that cytology testing does not significantly improve the accuracy of HPV testing, but it does increase costs and false-positive results.

Thousands of women's lives have been saved because the Pap test detected cervical cancer in its earliest stages. This would mean that a positive HPV screen could represent a false-positive cancer screen, as not all HPV infections progress to a cancer diagnosis - some of them clear on their own. As a result, the study's results are likely an underestimate, as underserved women were not included, although they may face the highest risk of developing cervical cancer, the authors said.

Most cases are preventable with screening the best way of catching it before it develops.

Hawaii governor signs first-ever bill banning sunscreens that harm coral reefs
At that rate, coral bleaching contributed to the loss of about half of the world's reefs in 2014 and 2015. The bill recognizes exceptions for people who are prescribed the sunscreens for medical needs.

While co-testing catches more precancerous cells, it also raises the incidence of false positives, points out Dr. Diane Harper, a professor of medicine who researches HPV at the University of MI.

This study selected a sample of women in British Columbia, placing 9,457 women in a control group to receive liquid-based cytology (LBC) testing and 9,552 in an intervention group to receive HPV testing. Then four years later, both groups were tested using both methods, in order to see the results.

In addition to finding more precancers in the initial screening, women who had the HPV test had a "significantly lower likelihood" of having precancer in the cervix when they exited the study four years later. Two years later, the ones that tested negative after the Pap smear had another test of the same type. The final round of co-testing found additional abnormal cells in some women who originally tested negative in both groups.

But in recent years, most medical groups have been recommending women get both tests, and some experts are pointing out that such so-called "co-testing" may be better than the HPV test alone at detecting precancerous changes; the study did find that in a small number of cases, Pap cytology identified precancerous lesions that HPV testing did not.

"At the moment, at most, we may be vaccinating at most 30 to 40 percent of girls". Also, there are various HPV DNA tests available globally, where a lot of them are FDA approved for detecting high risk HPVs. This type of cancer is mostly caused by the human papillomavirus (HPV), in as much as 99% of all cases.

Regime pounds south Syria after rebels say talks with Russian Federation 'fail'
Moscow had roundly rejected the terms and responded with a counter-proposal, the source said. President Donald Trump will have a detailed discussion about Syria when they meet in July.

Share